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Description
Human SHMT1 Antibody | 8832552-05171
Biological source
rabbit
Quality Level
100
Conjugate
unconjugated
Antibody form
affinity isolated antibody
Antibody product type
primary antibodies
Clone
polyclonal
Product line
Prestige Antibodies® Powered by Atlas Antibodies
Form
buffered aqueous glycerol solution
Species reactivity
human
Packaging
antibody small pack of 25 μL
Cytoplasmic serine hydroxymethyltransferase or SHMT1 regulates the biosynthesis of thymidylate in mammals. SHMT1 catalyzes the conversion of serine to glycine, which also results in the formation of 5,10-methylene-tetrahydrofolate.
Rises in SHMT1 activity have been linked to increased DNA synthesis in tumors and hence SHMT1 can have cancer therapeutic implications . Anti-SHMT1 antibody is specific for SHMT1 in humans.
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