ADORA2B (adenosine A2b receptor) is a G-protein coupled receptor. It is the most adenosine insensitive adenosine receptor. This gene is located on human chromosome 17p12-p11.2.
ADORA2B (adenosine A2b receptor) acts as a therapeutic target for cancer treatment. The tumor cells can use A2b receptor to induce progression. ADORA2B controls immune cell activity. It plays a major role in the transcriptional induction and protein stability of protein period 2 (Per2).
